ZHENG Lifei's Research Group


Group Name: Functional Biomacromolecular Materials Research Group

Profile: Dr. Lifei Zheng studied chemistry at Nanjing University (China). From 2010 to 2015 he pursued his graduate studies under the supervision of Prof. Andreas Herrmann at the Zernike Institute for Advanced Materials at the University of Groningen, The Netherlands. Then he moved to Radboud University as a postdoctoral researcher with Prof. Wilhelm Huck. Since 2018 Dr. Zheng was a project leader of the DWI Leibniz-Institute for Interactive Materials. Dr. Zheng has been working in the field of bio-inspired chemistry which is aiming to fabricate novel molecular architectures and systems by learning from nature’s elegance. His research work at this interface resulted in new biohybrid structures, novel catalytic strategies and integration of nature’s principle in artificial nanosystems, which are documented by several high-quality publications in leading chemistry journals, such as Nat. Chem., JACS and Angew. Chemie. He was awarded several prizes including Chinese Government Award for Outstanding Students Abroad (2014) and Lebniz leopodina fellow (2019). 

E-mail: zhenglf@ucas.ac.cn

Research area: Our group mainly focuses on the assembly of  functional biomacromolecular systems by means of bio-inspired and supramolecular strategies. The currently running projects in our lab including:
1) DNA hybrid materials: preparation, self-assembly properties and their biomedical applications;  
2) DNA-based dissipative self-assembly systems;
2) Assembly of recombinant proteins with tailor-made functionalities and their applications in the field of biomedicine.

Publications: 
1. M. Luo, M. Xuan, S. Huo, J. Fan, G. Chakraborty, Y. Wang, H. Zhao,* A. Herrmann,*, L. Zheng*, Angew. Chem. Int. Ed. 2020, 59, 59, 17250-17255.
2. L. Zheng#*, H. Zhao#, Y. Han#, H. Qian, J. Mecinović, L. Vukovic, P. Kral, W. Huck*, Catalytic transport of molecular cargo using diffusive binding along a polymer track. Nat. Chem. 2019, 11, 359-366.
3. L. Zheng#, S. Sonzini#, M. Ambarwati, E. Rosta, O. A. Scherman*, A. Herrmann*, Turning Cucurbit [8] uril into a supramolecular nanoreactor for asymmetric catalysis. Angew. Chem. Int. Ed. 2015, 54, 13007-13011.
4. L. Zheng, A. Marcozzi, J. Y. Gerasimov, A. Herrmann*, Conformationally constrained cyclic peptides: Powerful scaffolds for asymmetric catalysis. Angew. Chem. Int. Ed. 2014, 53, 7599 –7576. (rate as hot paper)
5. K. Liu#, L. Zheng#, Q. Liu, J. W. de Vries, J. Y. Gerasimov, A. Herrmann*, Nucleic acid chemistry in the organic phase: from functionalized oligonucleotides to DNA side chain polymers. J. Am. Chem. Soc. 2014, 136, 14255–14262. 
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